The Best Thanksgiving Turkey Sandwiches in 10 Minutes

Thanksgiving turkey sandwiches are the unsung hero of the holiday season—a delicious, satisfying creation that transforms yesterday’s feast into today’s favorite meal. These stacked beauties are loaded with tender turkey, creamy cranberry sauce, and all the fixings you love.

Here’s a fun fact: the day-after-Thanksgiving sandwich is so beloved that it inspired countless deli classics! This recipe is special because it takes just 10 minutes to assemble and uses ingredients you already have.

It’s perfect for busy families who want something quick yet incredibly flavorful. Much like our popular leftover turkey pot pie, this sandwich breathes new life into holiday leftovers.

What Are Thanksgiving Turkey Sandwiches?

Ever wonder why the sandwich you make the day after Thanksgiving tastes better than the actual turkey dinner? Maybe it’s the relaxed vibe, or perhaps it’s because you’re piling all those gorgeous flavors between two slices of bread without the pressure of hosting.

Thanksgiving turkey sandwiches are essentially edible hugs—comfort food that reminds you why you cooked that massive bird in the first place. As the saying goes, “the way to a man’s heart is through his stomach,” and these sandwiches prove it every single time. Ready to create sandwich perfection?

Why You’ll Love This Thanksgiving Turkey Sandwiches Recipe

The Ultimate Leftover Solution

These thanksgiving turkey sandwiches turn your refrigerator full of leftovers into a gourmet lunch that rivals any restaurant creation. The combination of moist turkey, tangy cranberry sauce, savory stuffing, and creamy mayo creates a flavor explosion in every bite. Each layer adds its own personality—the turkey brings protein and heartiness, the cranberry adds sweet-tart brightness, and the stuffing provides that comforting, herby crunch.

Budget-Friendly and Waste-Free

Making thanksgiving turkey sandwiches at home saves you from wasting precious leftovers and keeps your wallet happy. Instead of spending money on lunch out, you’re using ingredients you’ve already purchased. The average deli sandwich costs $12-15, but these homemade beauties cost just pennies per serving. Plus, you’re reducing food waste, which is a win for both your budget and the environment.

Customizable Flavor Bomb

The beauty of these sandwiches lies in their versatility. Load them up with crispy bacon, fresh lettuce, juicy tomatoes, or even a schmear of cream cheese. Want something similar but different? Check out our turkey club sandwich recipe for another delicious variation.

The toppings are limited only by your imagination—some folks add gravy-soaked bread, others prefer a spicy mustard kick. Whatever your preference, this sandwich delivers satisfaction every single time. Get creative in your kitchen and make this thanksgiving turkey sandwich your own masterpiece today!

How to Make Thanksgiving Turkey Sandwiches

Quick Overview

These thanksgiving turkey sandwiches are incredibly easy to make and deliver maximum flavor with minimal effort. They’re perfect for using up holiday leftovers without any complicated cooking techniques.

The combination of tender turkey, sweet cranberry sauce, savory stuffing, and creamy mayo creates an irresistible sandwich that tastes gourmet but comes together in minutes. The best part? You can customize every element to match your taste preferences.

Preparation Details:

• Prep Time: 10 minutes
• Cook Time: 0 minutes (or 5 minutes if toasting)
• Total Time: 10-15 minutes
• Servings: 4 sandwiches
• Difficulty Level: Easy

Key Ingredients for Thanksgiving Turkey Sandwiches

For the Sandwiches:

• 8 slices of bread (sourdough, whole wheat, or your favorite bakery bread)
• 1 pound leftover turkey (white and dark meat, sliced or shredded)
• 1 cup leftover cranberry sauce
• 1 cup leftover stuffing
• 4 tablespoons mayonnaise
• 2 tablespoons whole grain mustard (optional)
• 4 slices of cheese (Swiss, cheddar, or provolone)
• 1 cup fresh lettuce leaves
• 4 slices of tomato
• Salt and black pepper to taste

Optional Additions:

• 4 slices cooked bacon
• 1/4 cup leftover gravy
• 1 avocado, sliced
• Pickles or pickled onions
• Fresh herbs (parsley or thyme)

Step-by-Step Instructions

Step 1: Prepare Your Workspace

Clear your counter and gather all your ingredients. Take your leftover turkey out of the refrigerator and let it sit at room temperature for about 5 minutes. This ensures even warming if you choose to toast your sandwich. Arrange your bread slices, condiments, and toppings in an assembly-line fashion for easy sandwich building. If your stuffing is cold and firm, consider warming it slightly in the microwave for 20-30 seconds to make it easier to spread.

Step 2: Toast the Bread (Optional but Recommended)

Place your bread slices in a toaster, toaster oven, or skillet over medium heat. Toast until golden brown and slightly crispy, about 2-3 minutes per side if using a skillet. Toasting adds wonderful texture and prevents the bread from getting soggy from the cranberry sauce and mayo. If you prefer soft bread, you can skip this step entirely. For extra flavor, butter one side of each bread slice before toasting.

Step 3: Spread the Condiments

Take one slice of toasted bread and spread 1 tablespoon of mayonnaise evenly across the surface. On the other slice, spread about 2 tablespoons of cranberry sauce, making sure to reach all the corners. If you’re using mustard, mix it with the mayo before spreading for an extra tangy kick. The mayo creates a moisture barrier that protects the bread from getting soggy, while the cranberry sauce adds that signature sweet-tart flavor everyone loves.

Step 4: Layer the Turkey

On the mayo-covered bread slice, arrange about 4 ounces of turkey meat evenly. Make sure you’re using a good mix of white and dark meat for maximum flavor and moisture. Season lightly with salt and black pepper to enhance the turkey’s natural flavors. If your turkey seems dry, you can drizzle a tablespoon of leftover gravy over it or add an extra layer of mayo. Press down gently to ensure the turkey adheres to the bread.

Step 5: Add the Stuffing

Spread approximately 1/4 cup of leftover stuffing over the turkey layer. Use the back of a spoon to press it down gently, creating an even layer that won’t fall out when you bite into the sandwich. The stuffing adds incredible texture and those wonderful herb flavors that remind you of Thanksgiving dinner. If your stuffing contains sausage or other meats, it adds even more protein and flavor to your sandwich.

Step 6: Add Cheese and Vegetables

Place a slice of cheese on top of the stuffing. The cheese acts as another barrier and adds creamy richness. Layer on fresh lettuce leaves and a slice of tomato. The crisp vegetables provide a refreshing contrast to the rich, savory ingredients. If you’re using bacon, add 1-2 slices now for extra smoky flavor. The combination of warm and cold ingredients creates an amazing taste experience.

Step 7: Complete the Sandwich

Place the cranberry sauce-covered bread slice on top of your layered ingredients, sauce-side down. Press down firmly but gently to help everything stick together. If your sandwich is very tall, you can secure it with toothpicks to prevent it from falling apart. Cut the sandwich diagonally or straight down the middle—diagonal cuts make it easier to eat and look more appetizing on the plate.

Step 8: Serve Immediately

Transfer your thanksgiving turkey sandwich to a plate and serve right away for the best texture and temperature combination. If you’ve made multiple sandwiches, wrap any extras tightly in plastic wrap or aluminum foil and refrigerate for later. These sandwiches taste best when freshly made, but they’ll keep in the fridge for up to 6 hours before the bread starts getting too soft.

What to Serve Thanksgiving Turkey Sandwiches With

Classic Sides:

• Crispy sweet potato fries or regular french fries add a satisfying crunch
• Homemade coleslaw provides a cool, creamy contrast to the rich sandwich
• Leftover mashed potatoes can be formed into patties and pan-fried for potato cakes
• Pickles and pickled vegetables cut through the richness beautifully
• A simple green salad with vinaigrette balances the meal

Warm Comfort Options:

• A bowl of leftover turkey soup or chicken noodle soup makes this a complete comfort meal
• Leftover gravy served warm in a small bowl for dipping is absolutely divine
• Roasted Brussels sprouts or green beans add a healthy, flavorful element

Beverage Pairings:

• Hot apple cider (spiked or virgin) echoes the fall flavors
• Sparkling cranberry juice complements the cranberry sauce
• A crisp lager or wheat beer pairs wonderfully with the sandwich’s richness
• Hot tea or coffee if you’re enjoying this as a cozy lunch

Top Tips for Perfecting Thanksgiving Turkey Sandwiches

Bread Selection Matters

Choose a sturdy bread that can handle all those delicious layers without falling apart. Sourdough, ciabatta, and artisan whole wheat breads work beautifully because they have structure and flavor. Avoid thin sandwich bread that will get soggy quickly. If you prefer soft bread, consider using potato rolls or Hawaiian rolls for a slightly sweet contrast. Day-old bread actually works better than fresh because it’s slightly drier and toasts beautifully.

Temperature Control is Key

Don’t make the mistake of piling cold ingredients directly from the fridge onto your sandwich. Let your turkey come to room temperature for 5-10 minutes, or warm it gently in the microwave for 20-30 seconds. If you want a warm sandwich, heat the turkey and stuffing together, then assemble everything while they’re still warm. The cheese will melt slightly from the heat, creating an even better texture.

Balance Your Moisture

Too much cranberry sauce or mayo will make your bread soggy and create a messy sandwich. Use about 1-2 tablespoons of each condiment per sandwich. If you love extra sauce, serve it on the side for dipping instead of piling it all inside. The stuffing also adds moisture, so if yours is particularly moist, use a slightly smaller amount. Toast your bread to create a protective barrier against moisture.

Layer Strategically

The order of your ingredients matters for both structural integrity and flavor. Always put mayo or another spread directly on the bread first to create a moisture barrier. Place lettuce and tomatoes near the top of the sandwich to prevent them from making the bread soggy. Keep heavier, moister ingredients like turkey and stuffing in the middle where they’re supported by surrounding layers.

Customize for Dietary Needs

These sandwiches are incredibly adaptable. For a lighter version, skip the mayo and use Greek yogurt mixed with herbs. Use gluten-free bread for those with celiac disease or gluten sensitivity. Make it dairy-free by omitting the cheese or using vegan cheese alternatives. For a low-carb option, wrap all the ingredients in large lettuce leaves instead of bread.

Prevent Soggy Sandwiches

If you’re making sandwiches ahead of time, keep wet ingredients like tomatoes separate until serving time. Pack them in a small container and add them just before eating. Wrap sandwiches tightly in parchment paper rather than plastic wrap—it allows some air circulation. Store any extra cranberry sauce and gravy on the side rather than on the sandwich itself.

Elevate with Fresh Elements

Don’t rely solely on leftovers—fresh ingredients make a huge difference. Add crispy lettuce, ripe tomatoes, fresh herbs, or avocado slices to brighten up the flavors. A squeeze of fresh lemon juice over the turkey adds zing. Fresh cracked black pepper gives a pleasant heat that elevates every bite.

Storing and Reheating Tips

Refrigerator Storage:

Store assembled sandwiches wrapped tightly in plastic wrap or aluminum foil for up to 6 hours in the refrigerator. For best results, store the components separately and assemble sandwiches fresh when ready to eat. Keep sliced turkey in an airtight container for up to 4 days. Store cranberry sauce, stuffing, and other components in separate containers for up to 5 days. This method keeps ingredients at their peak freshness and prevents soggy bread.

Freezing Instructions:

While assembled sandwiches don’t freeze well due to the lettuce, tomatoes, and mayo, you can freeze the core components. Freeze sliced turkey in freezer bags with parchment paper between slices for up to 3 months. Stuffing freezes beautifully in airtight containers for up to 1 month. Cranberry sauce can be frozen for up to 2 months. Thaw all components overnight in the refrigerator before assembling your sandwiches.

Reheating Methods:

For the best warm sandwich experience, preheat your oven to 350°F. Wrap assembled sandwiches (without lettuce and tomato) in aluminum foil and warm for 10-12 minutes until heated through. Alternatively, use a panini press or skillet to create a crispy, grilled sandwich—cook for 3-4 minutes per side over medium heat. You can also reheat just the turkey and stuffing in the microwave for 30-45 seconds, then assemble with fresh cold ingredients.

Make-Ahead Strategy:

Prep all your components the night before and store them separately in the fridge. Toast your bread and let it cool completely, then store in a paper bag to maintain crispness. Slice your vegetables and store them in containers lined with paper towels to absorb excess moisture. In the morning, assembly takes just minutes for a quick, delicious lunch.

Frequently Asked Questions

Can I make Thanksgiving turkey sandwiches ahead of time?

Yes, but with some precautions. Assemble sandwiches no more than 6 hours before serving and wrap them tightly. For best results, keep wet ingredients like tomatoes separate and add them just before eating. Store in the refrigerator and bring to room temperature for 10 minutes before serving for better flavor.

What’s the best bread for turkey sandwiches?

Sourdough, ciabatta, and multigrain breads work exceptionally well because they’re sturdy enough to hold all the ingredients without getting soggy. Their slightly chewy texture and robust flavor complement the turkey perfectly. Avoid thin white bread unless you’re toasting it first. For a sweeter option, try Hawaiian rolls or brioche.

How do I keep my sandwich from getting soggy?

Toast your bread first to create a moisture barrier. Spread mayo or butter directly on the bread before adding other ingredients. Place lettuce leaves between wet ingredients and the bread. Avoid over-saucing with cranberry sauce or gravy. If making ahead, pack wet ingredients separately and add them just before eating.

Can I use deli turkey instead of leftover turkey?

Absolutely! While leftover Thanksgiving turkey has that special roasted flavor, quality deli turkey works perfectly fine. Choose thick-cut, premium deli turkey for the best texture and flavor. You can even warm it in a skillet with a bit of butter and herbs to give it more of that homemade taste.

What cheese works best on turkey sandwiches?

Swiss cheese is a classic choice because its mild, nutty flavor doesn’t overpower the turkey. Sharp cheddar adds a nice tang, while provolone is creamy and melts beautifully. Brie and gouda are gourmet options that pair wonderfully with cranberry sauce. Choose based on your personal preference—you really can’t go wrong.

How long do leftover turkey sandwiches last?

Assembled sandwiches should be eaten within 6 hours if kept at room temperature, or within 24 hours if refrigerated. Individual components last longer—turkey keeps for 3-4 days, stuffing for 3-5 days, and cranberry sauce for up to a week in the refrigerator. Always smell and inspect leftovers before using them.

Can I make these sandwiches vegetarian?

Yes! Replace the turkey with thick slices of roasted portobello mushrooms, marinated tofu, or a vegetarian turkey substitute. Use vegetable-based stuffing instead of traditional stuffing made with chicken or turkey stock. Keep all the other delicious components like cranberry sauce, cheese, and vegetables for a satisfying meatless version.

Should I warm up the turkey before making the sandwich?

This is personal preference. Many people love the contrast of warm turkey with cold, crisp vegetables. If you prefer everything warm, heat the turkey and stuffing together for 30-45 seconds in the microwave or warm them in a covered skillet over low heat. The cheese will melt slightly from the warmth, which is delicious.

What can I substitute for cranberry sauce?

Try cranberry relish, whole berry cranberry sauce, or even fig jam for a different flavor profile. Apple butter or pear chutney also work beautifully. Some people love using grape jelly for a sweeter option. Even a simple spread of honey mixed with Dijon mustard can replace the cranberry sauce while keeping that sweet-tangy balance.

How do I prevent the stuffing from falling out?

Warm your stuffing slightly so it’s more pliable and press it down gently onto the turkey layer. Cut your sandwich with a very sharp knife using a gentle sawing motion rather than pressing down hard. Toothpicks inserted through the sandwich help hold everything together. You can also spread the stuffing more toward the center, leaving the edges with just turkey and cheese.

Nutrition Information

Nutrient	Amount Per Serving
Calories	520
Total Fat	18g
Saturated Fat	5g
Cholesterol	95mg
Sodium	890mg
Total Carbohydrates	52g
Dietary Fiber	4g
Sugars	12g
Protein	38g
Vitamin A	8% DV
Vitamin C	6% DV
Calcium	15% DV
Iron	20% DV

Note: Nutrition information is approximate and based on one sandwich with standard ingredients. Values may vary based on specific ingredients used and portion sizes.

Tips for Avoiding Common Mistakes

Mistake #1: Using Dry Turkey

The biggest complaint about turkey sandwiches is dry meat. Avoid this by including both white and dark meat in your sandwich—dark meat is naturally more moist. If your turkey is dry, brush it lightly with gravy, drizzle with olive oil, or add extra mayo. Never use turkey that’s been refrigerated uncovered, as it dries out quickly.

Mistake #2: Overloading the Sandwich

While it’s tempting to pile everything on, an overstuffed sandwich falls apart and becomes difficult to eat. Aim for a sandwich that’s about 2-3 inches tall maximum. Use reasonable portions of each ingredient—about 4 ounces of turkey, 1/4 cup stuffing, and moderate amounts of sauce. Remember, you can always make a second sandwich!

Mistake #3: Skipping the Toast

Untoasted bread becomes soggy within minutes when it comes in contact with moist ingredients. Always toast your bread, even lightly, to create that protective barrier. The crispy texture also provides a pleasant contrast to the soft fillings. If you genuinely prefer soft bread, use very fresh, high-quality bread and eat the sandwich immediately.

Mistake #4: Cold Ingredients Straight from the Fridge

Serving your sandwich with ice-cold ingredients mutes the flavors significantly. Let ingredients sit at room temperature for 10 minutes, or warm the turkey and stuffing gently. Room temperature cheese melts slightly from body heat and warm ingredients, creating better texture. Cold mayo also spreads more easily when it’s not straight from the fridge.

Mistake #5: Cutting with a Dull Knife

A dull knife squashes your beautiful sandwich and causes all the ingredients to squeeze out the sides. Use a sharp serrated knife and cut with a gentle sawing motion. Clean the knife between cuts if you’re making multiple sandwiches. For very tall sandwiches, insert toothpicks before cutting to hold everything in place.

Mistake #6: Forgetting the Seasoning

Leftovers can taste bland when cold. Season your turkey layer with fresh cracked black pepper and a pinch of salt. Add fresh herbs like parsley or thyme for brightness. A squeeze of lemon juice can wake up tired flavors. Don’t rely solely on condiments for all your seasoning.

Mistake #7: Ignoring Texture Balance

A great sandwich has varied textures. If everything is soft, it becomes mushy and uninteresting. Include something crispy (toasted bread, lettuce, bacon), something creamy (mayo, cheese), something tender (turkey), and something with bite (stuffing). This variety makes each bite more enjoyable and satisfying.

Final Thoughts:

Thanksgiving turkey sandwiches are proof that sometimes the best meals come from the simplest ideas. These aren’t just sandwiches—they’re edible memories of your holiday gathering, packed between two slices of delicious bread. The beauty lies in their versatility and ease. You can make them exactly how you like them, and they’ll always taste like comfort and satisfaction.

Whether you’re enjoying one the day after Thanksgiving or making them throughout the week as leftovers dwindle, these sandwiches deliver every single time. Don’t be afraid to experiment with different breads, add unexpected ingredients, or create your own signature version.

Remember, the best thanksgiving turkey sandwich is the one that makes YOU happy. So pile on your favorite ingredients, take a big bite, and enjoy the fact that sometimes leftovers truly are better than the main event.

Pin this recipe, share it with friends who need leftover inspiration, and let me know in the comments what creative additions you make to your thanksgiving turkey sandwiches. Happy eating!